North Carolina Titer Testing

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Some North Carolina employers require antibody testing, also known as titer testing, as part of their pre-employment screening process. Existing employees may also be tested periodically as part of the process to ensure safety in the workplace, especially for industries such as healthcare or education. Titer testing is the first step to determining if someone is immune to certain diseases, such as varicella (Chickenpox), hepatitis A, hepatitis B, hepatitis C, measles, mumps, rubella, or COVID-19. If the antibody test indicates that an individual is not immune, Health Street can also provide services for vaccines and immunizations.

To register online for a titer test in North Carolina, simply click the "Register Now" button below. To schedule via phone or to contact us with questions regarding your antibody testing services, please reach us at (888) 378-2499.

Choose an Antibody Test in North Carolina

Assess a person's immunity to infectious diseases with the antibody testing options provided by Health Street in North Carolina. Find the right test for you below.

Hepatitis A Antibody Test

(starting at $179)

Assess hepatitis A immunity.


Hepatitis B Antibody Test

(starting at $199)

Determine immunity to hepatitis B.


Hepatitis C Antibody Test

(starting at $219)

Evaluate immunity to hepatitis C.


Triple Hepatitis Package

(starting at $549)

Test for immunity to hepatitis A, B, and C in one go.


MMR Titer

(starting at $249)

Check immunity to measles, mumps, and rubella.


Varicella Titer

(starting at $189)

Confirm immunity to Chickenpox (varicella virus).


Triple Antibody Package

(starting at $595)

Detect antibodies for hepatitis B, MMR, and varicella.


Total Antibody Package

(starting at $895)

Comprehensive antibody testing for hepatitis A, B, C, MMR, and varicella.


Search for Antibody Test By City, State, or ZIP

Overview of North Carolina Regulations

North Carolina Antibody Industry Regulations

North Carolina titer test regulations and vaccination laws do not require employers to ensure immunity or vaccination for contagious diseases. However, titer tests are available to determine immunity to these diseases among employees, ensuring a safe workplace.

Relevant North Carolina Laws, Acts, and Legislation

Executive Order No. 244 – Employees of North Carolina state cabinet agencies must be vaccinated for COVID-19 or otherwise undergo weakly testing for the virus.

Frequently Asked Questions

Does North Carolina require you to titer test?

North Carolina titer test regulations and vaccination requirements do not require titer testing or vaccinations for employees, with the exception of state cabinet employees that must be vaccinated for COVID-19. Also, North Carolina hospitals and other state healthcare facilities that receive federal Medicare and Medicaid assistance must require their staff to be immunized against COVID-19.

Although employers are not required to mandate other vaccinations among employees, facilities that work with vulnerable populations, such as hospitals, may require their staff to be immunized against certain infectious diseases. If that is the case, titer testing can often be used to ensure immunity from these contagious diseases in the workplace.

Certain North Carolina employers may choose to follow federal guidelines for titer tests and vaccinations. The federal Centers for Disease Control and Prevention (CDC) and the Occupational Safety and Health Administration have set guidelines for vaccinations and titer testing in the workplace.

What is different from federal regulations?

The CDC offers recommendations for industries at high risk for communicable diseases, such as healthcare. The CDC recommends these employees have immunity to or become vaccinated against the following diseases:

Hepatitis B
Measles, mumps, and rubella (MMR)
Tetanus, diphtheria, and pertussis (Tdap)

OSHA recommends that employees in high-risk industries, like healthcare, be vaccinated against COVID-19.

Why are antibody tests (titer tests) important?

Antibody (titer) tests are important for employers to ensure immunity to contagious diseases among their employees. Since vaccinations are not required in North Carolina, titer testing can help prevent disease outbreaks. Employees with negative titer tests should consider vaccination.

How much do antibody tests costs?

The cost of North Carolina antibody tests vary, depending on the disease being tested and the laboratory analyzing the test. Prices range from $100-$200 per test, and some testing companies offer discounted rates for multiple tests.

What is an antibody titer score? What is a good one?

The presence of antibodies in the blood means that an individual has immunity to the disease tested. A titer score is the number of antibodies, and the higher the score means the more antibodies are in the blood.

What do titer tests test for?

Titer tests check for the presence of antibodies to certain contagious diseases in the blood. Common titer tests include measles, mumps, rubella, tetanus, pertussis, diphtheria, hepatitis, meningitis, and COVID-19. The absence of antibodies in the blood means that an individual should consider vaccination.

What does a positive titer test mean?

A positive titer test means that antibodies to a particular disease were found in someone's blood. The presence of antibodies determines that a person has immunity to the disease that was tested. A negative test determines that a person is not immune.


"Executive Order No. 244." State of North Carolina Governor's Office, 4 January 2022,
Brigman, Lauren. "COVID-19 vaccine mandate for healthcare workers takes effect Thursday in North Carolina." WLOS ABC 13 News, 25 January 2022,
"COVID-19 Current Restrictions and Recommendations." State of North Carolina,
"State Immunization Laws for Healthcare Workers and Patients." Centers for Disease Control and Prevention (CDC),
"Recommended Vaccines for Healthcare Workers." Centers for Disease Control and Prevention (CDC),
"Protecting Workers: Guidance on Mitigating and Preventing the Spread of COVID-19 in the Workplace." United States Department of Labor, Occupational Safety and Health Administration (OSHA),
"Immunization Administration Requirements for State: NC." Centers for Disease Control and Prevention (CDC),