California Titer Testing

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Many industries, such as healthcare or education, will require proof of vaccination or immunity against certain diseases. Some people may have no proof of their immunity, or they may be uncertain about their vaccination status. For people who need to provide proof of immunity to an employer in California, Health Street offers antibody testing that can identify if a person has previously been infected with a specific disease or virus. We offer a variety of antibody testing services that can test for different antibodies, such as varicella (Chickenpox), hepatitis A, hepatitis B, hepatitis C, measles, mumps, rubella, or COVID-19.

Registering online for a titer test in California is easy. Simply click the "Register Now" button below. If you have questions regarding our services or would like to schedule your appointment via phone, we can also be reached at (888) 378-2499.

Choose Antibody Testing in California

Health Street provides a range of antibody testing options in California to help determine immunity to various diseases. See the available tests below.

Hepatitis A Antibody Test

(starting at $179)

Check a person's immunity to hepatitis A.


Hepatitis B Antibody Test

(starting at $199)

Find out if a person has immunity to hepatitis B.


Hepatitis C Antibody Test

(starting at $219)

Verify if a person has immunity to hepatitis C.


Triple Hepatitis Package

(starting at $549)

One test to check for immunity of hepatitis A, B, and C.


MMR Titer

(starting at $249)

Check if a person has immunity to measles, mumps, and rubella.


Varicella Titer

(starting at $189)

Determine if a person has immunity to Chickenpox (varicella virus).


Triple Antibody Package

(starting at $595)

Look for antibodies for: hepatitis B, measles, mumps, rubella, and varicella.


Total Antibody Package

(starting at $895)

The most comprehensive antibody testing package: hepatitis A, B, and C, measles, mumps, rubella, and varicella.


Search for Antibody Test By City, State, or ZIP

Overview of California Regulations

California Antibody Testing Regulations

While there are no general vaccination or California antibody test regulations for adults, the California Department of Public Health refers to the CDC's recommended guidelines regarding immunization guidelines for adults aged 19 and over.

The state of California does not require vaccinations for college-aged children but has provided recommendations for California colleges and universities with campus housing to follow. Each school can set its own requirements, and many allow for a California titer test when vaccination records are not available.

California Antibody Industry Regulations

In the state of California, employees working in certain industries must show proof of immunity to specific diseases, either by providing vaccination records or California titer test results. Under current California laws, employers must offer healthcare workers and ambulatory care employees access to vaccinations. Under California law, all workers in California healthcare facilities are now also required to be fully vaccinated against COVID-19, including a booster when appropriate.

The U.S. Equal Employment Opportunity Commission has stated that in light of current CDC Interim Guidelines, the Americans with Disability Act (ADA) does not allow employers to require antibody testing before allowing employees to work. In light of this, there are no California antibody test regulations that allow for mandated COVID-19 antibody testing.

Relevant California Laws, Acts, and Legislation

Cal. Code Regs. tit. 8, § 5193 - requires employers to offer Hepatitis B vaccinations to all employees whose daily tasks create a potential for occupational exposure to the disease unless the employee has already been vaccinated, has antibody titer test results proving immunity, or has a medical exemption.
Cal. Health & Safety Code § 1288.7 (2007) - requires acute care hospitals to offer employees influenza vaccines annually at no cost and require employees to accept the vaccination or declare in writing that he or she has declined it.
Cal. Code Regs. tit. 8, § 5199 - requires hospitals, skilled nursing facilities, clinics, medical offices, and other outpatient medical facilities to offer seasonal influenza vaccines to all employees with occupational exposure. If an employee declines, he or she must sign an influenza vaccine declination statement.
EO 803 - Beginning with the Fall 2022 semester, a major California University has adopted an executive order requiring all students to be up to date on specific immunizations. Either vaccination records or the date and result of California antibody testing are acceptable proof of immunization.

Frequently Asked Questions

What does a positive titer test mean?

If a titer test is "positive," it means that the individual taking the test has immunity to the disease. In certain situations, California titer test regulations allow individuals to submit a positive titer test instead of a vaccination record.

Does California require you to test?

In some situations, California antibody test regulations allow titer testing if vaccination records are not available. However, if an individual can submit vaccination records, titer testing is not required.

Why are antibody tests important?

Antibody testing can determine if a person has immunity against certain diseases. This process may be necessary for those who are unsure of their vaccination status, or for employers that require proof of immunity to diseases. Testing for antibodies in the blood is also commonly performed to avoid unnecessary vaccinations for someone who has already developed immunity.

How much do antibody tests (titer tests) cost?

This depends on which type of antibody test is ordered. Health Street offers a variety of individual antibody testing services as well as package deals. For a comprehensive list of antibody tests and pricing, take a look at our antibody test registration page.

How long are titer tests good for?

Titer test results are records of whether a person has tested positive or negative for immunity against certain diseases. Depending on the type of disease, some employers may require employees to periodically test for antibodies, and may require employees to receive certain vaccinations before they are permitted to work. The frequency of testing depends on many factors, including the industry and the type of disease or vaccine. For more information about specific diseases and the recommended vaccine schedule, try taking a look at our Vaccines & Immunizations page.


"Shots for School: Shots for College." California Department of Public Health,
"New Immunization Requirements for All CSU Students." California State University, 21 August 2019,
"Immunization Requirements and Recommendations." California State University,
"Immunization Requirements." California State University,
"State Immunization Laws for Healthcare Workers and Patients - CA." Centers for Disease Control and Prevention (CDC),
"EEOC Issues Updated COVID-19 Technical Assistance Publication Addressing Antibody Testing." U.S. Equal Employment Opportunity Commission (EEOC), 17 June 2020,
California Department of Public Health,
"Recommended Adult Immunization Schedule for ages 19 and older, United States, 2021." Centers for Disease Control and Prevention (CDC),
"Health Care Worker Vaccine Requirement." California Department of Public Health, 25 January 2022,
"Cal. Code Regs. tit. 8, § 5193. Bloodborne Pathogens." California Department of Industrial Relations,
"Cal. Health & Safety Code § 1288.7. Hospital Infectious Disease Control Program." California Legislature,
"Cal. Code Regs. tit. 8, § 5199. Aerosol Transmissible Diseases." California Department of Industrial Relations,
"Executive Order 803. Immunization Requirements and Recommendations." The California State University, 25 March 2019,